Study of pathogenetic mechanism of atypical inflammation caused by bronchial asthma in children and choosing of necessary treatment method is very relevant today. Heterogeneous nature of pathogenesis of disease is explaned as combination of immunological and non-immunological mechanisms in it. Thus, in bronchial asthma, Vitamin D supply is very necessary for formation of adequate immune reaction and significant in the pathogenesis of disease. It can be interpreted in result of correlation analysis of indicators received from the submitted scientific work that, amount of vitamin D in blood serum has direct correlation with the increase of rate of allergy and asthma. And this is evaluated by the improvement of the clinical effectiveness of the individual approach to the treatment of bronchial asthma, as well as the extension of the remission period.
Фассахов Р.С. Успех в терапии тяжелой бронхиальной астмы: правильный выбор биологического препарата у правильно
подобранных больных. // – Москва: Медицинский Совет. – 2019. No15, – c. 22-28
Потрохова Е.А. Бехчета-подобный семейный аутовоспалительный синдром / Е.А.Потрохова, Л.С.Балева, А.Е.Сипягина // –
Москва: Российский вестник перинатологии и педиатрии. – 2021. No2, – p. 110-115
Савушкина Е.Ю., Хаитов М.Р. Особенности молекулярных механизмов патогенеза бронхиальной астмы в сочетании с полипозным риносинуситом. // – Москва: Пульмонология. – 2021. No1, – c. 7-19.
Громова, О.А. Метаболиты витамина D : роль в диагностике и терапии витамин D- зависимой патологии / О.А.Громова,
И.Ю.Торшин, И.К.Томилов [и др.] // Практическая медицина. – Казань: – 2017. – No 5 (106). – c. 4–10.
Захарова И.Н. Известные и неизвестные факты о витамине D / И.Н.Захарова С.В.Яблочкова, Ю.А.Дмитриева [и др.] //
Вопросы современной педиатрии. – Москва: –2017. – No 12 (2). – С. 26–31.
Sassi, F. Tamone C., Amelio P. Vitamin D: nutrient, hormone, and immunomodulator / // Nutrients. – 2018. 10(11), – p. 1656.
Bartley J.R. Vitamin D, innate immunity and upper respiratory tract infection // J. Laryngol Otol. – 2018. 124 (5). – p. 465–469.
Gil A., Plaza-Diaz J., Mesa M. Vitamin D: Classic and Novel Actions // Ann Nutr. Metab. – 2018. 72 (2). – p. 87–95.
Leiter K., Franks K., Borland M. Vitamin D receptor polymorphisms are associated with severity of wheezing illnesses and asthma
exacerbations in children // J. Steroid BiochemMol Biol. – 2020. 201. – p. 105–692.
Zhao D. Association of vitamin D receptor gene polymorphisms with susceptibility to childhood asthma: A meta-analysis [Text] / D.Zhao, D.Yu, Q.Ren, B. [et al.] // Pediatr. Pulmonol. – 2017. 52 (4)? – p. 423–429