COMPARATIVE ANALYSIS OF MYCOLOGICAL FEATURES OF THE SKIN MICROBIOME IN INDIVIDUALS WITH BAD HABITS
Abstract
The work was carried out with the aim of comparative study of mycological features of the skin in drug addicts and alcoholics. The study included 31 healthy individuals, 43 drug addicts and 48 alcoholics.
According to the results of the research, dangerous fungi of the genus C. krusei, Mucor, Rhizopus, Absidia, Pensillosis, P. notatum were not detected on the skin of healthy people. C.tropicis is statistically significantly higher in alcoholics than in healthy individuals (p=0,0014, p>0,005, xi2 = 10.26). Although other fungal species were more common in alcoholics than in healthy individuals, the differences were not statistically significant. Among drug addicts, fungi of the genus C. tropicalis (p=0,0041, p>0,005, xi2=8,23) and Cryptococcus (p=0,002, p>0,005, xi2=9,53) were statistically significantly more common than in healthy individuals.
Although there was no statistical significance in the frequency of occurrence of other fungal genera in drug addicts and alcoholics, all fungi were more common. Only fungi of the genus C. tropicalis were more common in alcoholics (48%) than in drug addicts (44%). It has been established that harmful and lifethreatening habits, such as drug and alcohol addiction, pose a serious threat to the skin microbiome.
References
Захарова И.Н., Касьянова А.Н. Микробиом кожи: что нам известно сегодня? // Медицинский совет, – 2019, №17, – с. 168-176.
Grice E.A. A diversity profile of the human skin microbiota / Grice E.A., Kong H.H., Renaud G. [et al.] // Genome Res., – 2008, 18 (7), – p. 1043-1045 doi: 10.1101/gr.075549.107
Sender R., Fuchs S., Milo R. Revised estimates for the number of human and bacteria cells in the body // PLoS Biol., – 2016, 14(8), – p.1-14. doi: 10.1371/journal.pbio.1002533.
Baldwin H.E. The Role of Cutaneous Microbiota Harmony in Maintaining a Functional Skin Barrier / H.E.Baldwin,
N.D.Bhatia, A.Friedman [et al.] // J Drugs Dermatol., – 2017, 16(1), – p. 12-18.
Николов В.В. Микрофлора наружного покрова в норме и при рожистой инфекции // Клиническая иммунология, аллергология, иммунитет, – 2015, 7(86). – c. 9-12.
Рахматов Т.П., Рахматов А.Б., Курбанова Н.К. Наружная терапия хронических дерматозов, ассоциированных с инфекциями кожи // Дерматовенерология и эстетическая медицина, – 2019, 3(43), – c. 156.
Саипова Н.С., Тохтаев Г.Ш. Микробиота кожи и ее роль при дерматологических заболеваниях у больных туберкулезом легких // Universum: химия и биология, – 2020, № 8, – с.8-14
Grice E.A., Segre J.A. The skin microbiome. // Nat Rev Microbiol. – 2011, 9 (4), – p. 244- 253.doi: 10.1038/nrmicro2537.
Миннебаев Р.Х. Наркотизация как фактор преступности // Юридическая наука и практика // Вестник Нижегородской академии МВД России, – 2014, №4, – c. 145-150
Бахтеев С.С. Проблемы алкоголизма и преступности // Правопорядок: история. теория. Практика, – 2014, №1, – с.101-103.
Fierro F. Penicillium chrysogenum, a Vintage Model with a Cutting-Edge Profile in Biotechnology / F.Fierro, I.Vaca, N.I. Castillo [et al.] // Microorganisms, – 2022, 10(3), – p. 573 doi: 10.3390/microorganisms10030573.
Keywords
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.